Oxygen saturation in adolescent high-altitude residents, implications for clinical decision-making

Authors

DOI:

https://doi.org/10.35319/conr.20268147

Keywords:

Oxygen saturation, pulse oximetry, adolescent, environmental hypoxia, altitude, reference values

Abstract

In high-altitude cities such as El Alto (4150 meters above sea level), reference values established at sea level are still applied, which can lead to misdiagnosis, overestimation of respiratory pathologies and clinical decisions with direct repercussions on nursing care. A quantitative, descriptive and cross-sectional study was carried out in 94 adolescents living permanently in El Alto, selected under inclusion and exclusion criteria (absence of acute respiratory infection, anemia, lung disease, pregnancy and tobacco use). Oxygen saturation was measured by non-invasive digital pulse oximetry, after three minutes of rest and with three consecutive readings, registering the most stable value. 71 % were 14 years old; 60 % male, 40 % female. The saturations at rest were; 47 % between 91-95 %, 42 % between 86-90 %, 7% between 80-85 % and 2 % between 96-100 %. The average was 88.2 % in 14-year-olds, 91.3 % in 15-year-olds, and 95% in 16-17-year-olds. The heart rate was between 91-100 bpm in 21 % of cases, and only 2 % reported a respiratory history. Most of them had saturations between 88 and 95 %, values compatible with a physiological adaptation to chronic hypobaric hypoxia typical of extreme altitude. These evaluations show the need to have contextualized reference values for populations living at high altitudes, avoiding inappropriate clinical interpretations and optimizing care decision-making.

Downloads

Download data is not yet available.

Author Biographies

Loreley Mijaela Quenta Quispe, Ministerio de Salud y Deportes. Servicio Departamental de Salud

Ministerio de Salud y Deportes. Servicio Departamental de Salud- La Paz. Hospital del Niño “Dr. Ovidio aliaga Uría”. Unidad de Cuidados Intensivos en Pediatría. Pasaje Mayor Zubieta #100. Zona de Miraflores. La Paz - Estado Plurinacional de Bolivia

Yhissel Mamani Mamani, Ministerio de Salud y Deportes. Servicio Departamental de Salud

Ministerio de Salud y Deportes. Servicio Departamental de Salud- La Paz. Hospital del Niño “Dr. Ovidio aliaga Uría”. Unidad de Cuidados Intensivos en Pediatría. Pasaje Mayor Zubieta #100. Zona de Miraflores. La Paz - Estado Plurinacional de Bolivia

Soledad Etelvina Quispe Apaza, Universidad Católica Boliviana San Pablo

Universidad Católica Boliviana San Pablo. Dirección General de Unidades Académicas Campesinas. Unidad Académica Campesina de Pucarani. Enfermería. Provincia Los Andes – Pucarani. Av. Avaroa s/n. La Paz - Estado Plurinacional de Bolivia.

References

Guyton AC, Hall JE. Transporte de oxígeno y dióxido de carbono en la sangre y los líquidos corporales. En: Tratado de Fisiología Médica. 13.ª ed. Madrid: Elsevier; 2017. p. 503-20.

Hall JE. Regulación de la respiración y transporte de oxígeno. En: Guyton y Hall. Fisiología Médica. 14.ª ed. Barcelona: Elsevier; 2021. p. 529-45.

Wukitsch MW, Petterson MT, Tobler DR, Pologe JA. Pulse oximetry: analysis of theory, technolo-gy, and practice. J Clin Monit 1988;4(4):290-301. DOI: https://doi.org/10.1007/BF01617328

Severinghaus JW, Naifeh KH. Accuracy of response of six pulse oximeters to profound hypoxia. Anesthesiology 1987;67(4):551-8. DOI: https://doi.org/10.1097/00000542-198710000-00017

Ralston AC, Webb RK, Runciman WB. Potential errors in pulse oximetry. I. Pulse oximeter evalua-tion. Anaesthesia 1991;46(3):202-6. DOI: https:// doi.org/10.1111/j.1365-2044.1991.tb09410.x

Jubran A. Pulse oximetry. Intensive Care Med 2004;30:2017-20. DOI: https://doi.org/10.1007/s00134-004-2399-x

Subhi R, Smith K, Duke T. When should oxygen be given to children at high altitude? A systematic review to define altitude-specific hypoxaemia. Arch Dis Child 2009;94(1):6-10. DOI: https://doi.org/10.1136/adc.2008.138362

West JB. Oxygen transport at high altitude. In: High Altitude Medicine and Physiology. 5th ed. Boca Raton: CRC Press; 2013. p. 25-52.

Gamponia MJ, Babaali H, Yugar F, Gilman RH. Reference values for pulse oximetry at high altitude. Arch Dis Child 1998;78(5):461-5. DOI: https://doi.org/10.1136/adc.78.5.461

McCollum ED, King C, Deula R, Zadutsa B, Mankhambo L, Nambiar B, et al. Pulse oximetry for children with pneumonia treated as outpatients in rural Malawi. Bull World Health Organ 2016; 94(12):893-902. DOI: https://doi.org/10.2471/BLT.16.173401. Erratum in: Bull World Health Organ. 2017;95(1):81. DOI: https://doi.org/10.2471/BLT.17.100117

Vargas E, Spielvogel H. Chronic mountain sickness, optimal hemoglobin, and heart disease. High Alt Med Biol. 2006;7(2):138-49. DOI: https://doi.org/10.1089/ham.2006.7.138

Grimm M, Seglias A, Ziegler L, Mademilov M, Isaeva E, Tynybekov K, et al. Sleep apnea in school-age children living at high altitude. Pulmonology 2023;29(5):385-91. DOI: https://doi.org/10.1016/j.pulmoe.2023.02.008

Beall CM. Adaptation to high altitude: Phenotypes and genotypes. Annu Rev Anthropol 2014;43: 251-72. DOI: https://doi.org/10.1146/annurev-anthro-102313-030000

Arias-Stella J, Recavarren S. The pulmonary circulation at high altitudes. Circulation. 1962;26: 915-22. DOI: https://doi.org/10.1161/01.CIR.26.6.915

Mortola JP. Children’s breathing at high altitude. Respir Physiol Neurobiol. 2007;158(2-3):123-30. DOI: https://doi.org/10.1016/j.resp.2007.04.009

Andrade V, Andrade F, Riofrio P, Nedel FB, Martin M, Romero-Sandoval N. Pulse oximetry curves in healthy children living at moderate altitude: a cross-sectional study from the Ecuado-rian Andes. BMC Pediatr 2020;20(1):440. DOI: https://doi.org/10.1186/s12887-020-02334-z

Ucrós S, Granados CM, Castro-Rodríguez JA, Hill CM. Oxygen saturation in childhood at high altitude: a systematic review. High Alt Med Biol 2020;21(2):114-25. DOI: https://doi.org/10.1089/ham.2019.0077

Tüshaus L, Moreo M, Zhang J, Hartinger SM, Mäusezahl D, Karlen W. Physiologically driven, altitude-adaptive model for the interpretation of pediatric oxygen saturation at altitudes above 2,000 m a.s.l. J Appl Physiol 2019;127(3):847-57. DOI: https://doi.org/10.1152/japplphysiol.00478.2018

Saturación de oxígeno en adolescentes residentes de gran altitud, implicancias para la toma de decisiones clínicas

Published

2026-07-07

How to Cite

Quenta Quispe, L. M., Mamani Mamani, Y., & Quispe Apaza, S. E. (2026). Oxygen saturation in adolescent high-altitude residents, implications for clinical decision-making. Current Opinion Nursing & Research, 8(1), 15–21. https://doi.org/10.35319/conr.20268147

Issue

Section

Research Note