Microbiota intestinal. Un indicador que repercute en la salud humana
Resumen
El intestino humano es considerado un órgano complejo dadas las funciones que desempaña, y el gran número de géneros y especies bacterianas que alberga en su interior. Se ha postulado que el "tracto intestinal (TI) tiene la más abundante y diversa población de bacterias del cuerpo humano", formando un reservorio con una superficie interna de 200 m2 aproximadamente, 100 veces la superficie del área de la piel.
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Castañeta C. Ecosistema Intestinal. México DF; 2012. p. 11-8.
Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial mutualism in the human intestine. Science 2005;307(5717):1915-20. DOI: https://doi.org/10.1126/science.1104816
Samuel BS, Shaito A, Motoike T, Rey FE, Backhed F, Manchester JK, et al. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci USA 2008;105(43):16767-72. DOI: https://doi.org/10.1073/pnas.0808567105
Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 2004;101(44):15718-23. DOI: https://doi.org/10.1073/pnas.0407076101
Cani PD, Bibiloni R, Knauf C, Waget A, Neyrinck AM, Delzenne NM, et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008;57(6):1470-81. DOI: https://doi.org/10.2337/db07-1403
Gill SR, Pop M, Deboy RT, Eckburg PB, Turnbaugh PJ, Samuel BS, et al. Metagenomic analysis of the human distal gut microbiome. Science 2006;312(5778):1355-9. DOI: https://doi.org/10.1126/science.1124234
Barbara G, Stanghellini V, Brandi G, Cremon C, Di Nardo G, De Giorgio R, et al. Interactions between commen-sal bacteria and gut sensorimotor function in health and disease. Am J Gastroenterol 2005;100(11):2560-8. DOI: https://doi.org/10.1111/j.1572-0241.2005.00230.x
Sekirov I, Russell SL, Antunes LC, Finlay BB. Gut microbiota in health and disease. Physiol Rev 2010;90(3): 859-904. DOI: https://doi.org/10.1152/physrev.00045.2009
Lu S, Cai Y. Bacterial molecular syringe for drug delivery. Cell Host Microbe 2023;31(6):917-9. DOI: https://doi.org/10.1016/j.chom.2023.05.005
Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, et al. Population-based meta-genomics analysis reveals markers for gut microbiome composition and diversity. Science 2016;352(6285):565-9. DOI: https://doi.org/10.1126/science.aad3369
Guarner F. Papel de la flora intestinal en la salud y en la enfermedad. Nutr Hosp 2007;22(Suppl 2):14-9.
Koszewicz M, Jaroch J, Brzecka A, Ejma M, Budrewicz S, Mikhaleva LM, et al. Dysbiosis is one of the risk factor for stroke and cognitive impairment and potential target for treatment. Pharmacol Res 2021;164:105277. DOI: https://doi.org/10.1016/j.phrs.2020.105277
Bai J, Hu Y, Bruner DW. Composition of gut microbiota and its association with body mass index and lifestyle factors in a cohort of 7-18 years old children from the American Gut Project. Pediatr Obes 2019;14(4):e12480. DOI: https://doi.org/10.1111/ijpo.12480
Singh RK, Chang HW, Yan D, Lee KM, Ucmak D, Wong K, et al. Influence of diet on the gut microbiome and implications for human health. J Transl Med 2017;15(1):73. DOI: https://doi.org/10.1186/s12967-017-1175-y
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Derechos de autor 2026 Current Opinion Nursing & Research
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.
